Some sources claim that there is a strong Vitamin C B12 antagonism, and that supplementing large amounts of Vitamin C will inhibit Vitamin B12. While possible in theory, it generally does not happen in practice since Mineral Ratios are subject to neurological and structural control. However out of interest, Dr. Ronald Roth checked the chemical profiles of patients who either had Vitamin B12 or Vitamin C injections, since theoretically that might have had the most pronounced effect, but there were no short-term or long-term changes in the other. Since an inhibiting effect can take place during intestinal uptake, Dr. Ronald Roth also checked for any interactions with very high oral intake, but there were again no apparent or conclusive patterns to confirm this... Full Text